Subject Classification /Topics

Subject classifications and topics suitable for FGTE 2025, based on the conference’s focus on gene therapy, gene editing, and related fields:

1. Gene Therapy & Gene Editing

  • CRISPR/Cas9, TALENs, ZFNs, and base editing technologies
  • Epigenome editing and regulation
  • Prime editing and next-gen gene editing tools
  • Gene silencing and RNA interference (RNAi)
  • Delivery methods: viral vs. non-viral vectors
  • In vivo vs. ex vivo gene editing approaches
  • Safety, efficacy, and off-target effects in gene therapy
  • Gene editing for rare and monogenic diseases
  • Ethical, regulatory, and clinical challenges in gene editing

2. Synthetic Biology & Genome Engineering

  • Synthetic gene circuits and networks
  • Directed evolution and protein engineering
  • Designer transcription factors and switches
  • Synthetic biology applications in gene and cell therapy
  • Gene circuits for disease modeling and drug screening
  • Applications in agriculture and industrial biotechnology

3. Molecular Biology & Regenerative Medicine

  • DNA/RNA-based therapeutics
  • Stem cell gene editing and therapy
  • Tissue regeneration and repair
  • Gene-based approaches for regenerative medicine
  • Organoids and 3D tissue models in research

4. Clinical Applications & Translational Research

  • Gene therapy in oncology (CAR-T cells, TCRs, etc.)
  • Hematologic and immunologic disorders
  • Neurological and neurodegenerative diseases
  • Gene editing for cardiovascular and metabolic diseases
  • Cell and gene-based immunotherapy
  • Clinical trials and case studies in gene therapy

5. Biotechnology & Bioengineering

  • Advances in vector design and delivery systems
  • Bioproduction and large-scale manufacturing of gene therapies
  • Biomaterials for gene delivery
  • CRISPR screens for functional genomics
  • Bioinformatics and AI in gene therapy design

6. Emerging Technologies & Innovations

  • Epitranscriptomics and RNA modifications
  • CRISPR diagnostics and therapeutics
  • Multi-omics approaches (genomics, transcriptomics, proteomics)
  • Genome writing and synthetic genomics
  • Gene therapy for aging and longevity research

7. Ethical, Regulatory, and Societal Issues

  • Gene editing ethics and human germline modification
  • Regulatory frameworks and clinical trial challenges
  • Public perception and acceptance of gene editing
  • Bioethics and patient consent in gene therapy trials

8. Tools & Techniques

  • High-throughput screening for gene editing
  • Next-gen sequencing (NGS) and its applications
  • Single-cell omics in gene therapy research
  • Computational modeling and AI for gene editing design
  • Imaging and visualization techniques in molecular biology